hhmi cancer activity

It is caused by uncontrolled division of abnormal cells and can occur anywhere in the body. Experience with planning and organizing team functions and coordinating ongoing team activity. Combinations of the risk factors listed above work together to produce (or avoid) the development of cancer, determining the kind of cancer that develops as well as the speed of its growth.

��k� qR�0��/�Bg��Y��i��YQE��eȿ:�Ul6#�_��[�f՛[|Zf�5�� B��8`��J%?�}Q�I�bi&��`��H�w!�[&�ͽF"��d-��T�"��d#�K��][��u��֊D��s>j��A��J� .��ZY��٪�E"�_�@!IR.��A��DkUpt��m�-��8U��%�.��L�؏ These card images are licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CCC BY-NC-SA 4.0) license. They will complete and interpret a pedigree, build understanding of genetic counseling and genetic testing and simulate gel electrophoresis. Teaching Cell Biology and Genetics Using Cancer, Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International, Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International license, Activity 1 and 2 Overview - Teachers (PDF), Activity 1 and 2 Overview - Teachers - Español (PDF), Activity 1 and 2 Documents - Español (ZIP), Cancer group finds biggest one-year drop in U.S. death rate, Blood test helped detect cancer before symptoms, study finds, Guidelines say more women may need breast cancer gene test, Breast cancer risk from menopause hormones may last decades, Efficacy of a Medication for Chronic Myeloid Leukemia, Cancer and Cell Fate in the Intestinal Epithelium. In “Activity 1,” students identify where genes involved in cancer are located on human chromosomes, using a set of 139 cards and associated posters. Students investigate genetics to understand the causes of cancer using information on Steve and Nikki’s family health history. More information about the lab can be found here: https://www.plant-stomata.org/. The position requires mobility, including the ability to move materials weighing up to several pounds (such as a laptop computer or tablet). It features annotated primary literature about cancer, a hands-on data activity, and other resources from throughout the web. Compiling and maintaining critical lab databases and inventories of equipment and materials to support the lab’s functions and. Hear how educators are using BioInteractive content in their teaching. HHMI believes every student and citizen can experience science in a meaningful way.

Mary Wuerth explains how she uses the BCR-ABL Click & Learn to teach the importance of protein structure in understanding how proteins work, and how scientists use that knowledge to design drugs to fight cancer.

The Science in the Classroom Cancer collection will help you begin to explore the latest findings in cancer research.

In “Activity 1,” students identify where genes involved in cancer are located on human chromosomes, using a set of 139 cards and associated posters. about Expanding Access to New Tools to Study Childhood Cancers, about Programming the Immune System to Attack Tumors, about William Kaelin Receives Lasker Basic Medical Research Award, about Undruggable Mutation Meets Its Match, about A Constellation in the Chaos of Cancer Chromosomes, about Bad to the Bone: Some Breast Cancer Cells Are Primed to Thrive, about Fármaco prolonga la supervivencia de pacientes con cáncer de próstata resistente a medicamentos, about Chromatin May Explain How Few Genetic Changes Lead to Pediatric Kidney Cancer, about Picking Cancer Stem Cells Out of the Crowd, Expanding Access to New Tools to Study Childhood Cancers, Programming the Immune System to Attack Tumors, William Kaelin Receives Lasker Basic Medical Research Award, A Constellation in the Chaos of Cancer Chromosomes, Bad to the Bone: Some Breast Cancer Cells Are Primed to Thrive, Fármaco prolonga la supervivencia de pacientes con cáncer de próstata resistente a medicamentos, Chromatin May Explain How Few Genetic Changes Lead to Pediatric Kidney Cancer, Picking Cancer Stem Cells Out of the Crowd. Visualize genetic data (Activity 1 only). The selected Lab Manager will be responsible for: Compiling and maintaining critical lab databases and inventories of equipment and materials to support the lab’s functions and organizing and managing daily operations of the lab’s plant science research program. © 2020 Springer Nature Limited. Coordinate utilization by the lab of University core services such as sequencing and use of greenhouse facilities. 's��2� Mammalian pyruvate kinase catalyzes the final step of glycolysis, and its M2 isoform (PKM2) is widely expressed in proliferative tissues. Abstract: Over the past decade, comprehensive sequencing efforts have revealed the genomic landscapes of common forms of human cancer.For most cancer types, this landscape consists of a small number of “mountains” (genes altered in a high percentage of tumors) and a much larger number of “hills” (genes altered infrequently).

Small-group work spurs discussion about the genes that are mutated in different types of cancers and the cellular processes that the affected genes control. Data Points.

A document within the ZIP file contains suggestions for their use. In this activity you will examine the locations throughout the genome of genes that when mutated cause cancer to develop (i.e., cancer genes) and you will learn about the normal functions of these genes.

We would ask that you attribute these to BioInteractive and not use them for commercial purposes. :�}_�dU!��H��ӥ��H��R(��h~�� +��)��\��R��0�~� "/�iT��#��H^�J�M�I�Y�DF�p�&o��"і|�Z�Z1��99��"|��*3s�d�0+M�j �c�`��F§6�|�o,�#�7-l��S��$��. “Cancer Genome Landscapes.” Science 339, 6127 (2013): 1546–1558. After watching a short video and completing a worksheet, students can do one or both of the following activities. Organize and manage day-to-day lab functions as well as special projects as assigned; Develop, implement and maintain efficient operating procedures and laboratory practices; Maintain current knowledge of applicable health and safety regulations by interacting with designated University managers; monitor lab practices and take appropriate measures to assure continuous compliance; Orient and train all personnel on lab safety, appropriate conduct, operating standards, and technical and administrative practices; Oversee operation and maintenance of essential equipment and maintain all service records and contracts; Maintain appropriate inventories of supplies and materials; purchase all supplies, materials, lab services, and equipment; manage vendor relationships, and monitor expenditures; Oversee organization and storage of research materials, including cells, seeds, and clones; develop and maintain electronic inventory systems for all materials; verify materials to be shipped to other researchers, and oversee verification, recording, and storage of materials received from others; handle routine processes associated with Material Transfer Agreements (MTAs); Perform assigned research tasks, such as: genotyping plants; transforming and caring for rare, transgenic, and mutant plants to promote seed propagation; constructing, isolating and analyzing plasmids; expressing and purifying recombinant proteins; using basic and advanced microscopy to characterize plant phenotypes and fluorescence protein/dye expression patterns. High School — AP/IB. �@�;�� Evaluate new materials, research methods, computer systems, and equipment and coordinate implementation as directed. College.

The “Activity 1 and 2 Overview” document provides short summaries of the two activities, along with key concepts and learning objectives, background information, references and rubrics, and answers to students’ questions. HHMI shares the latest on our research, education, and organizational news. Scientists are employed by HHMI and conduct their work at HHMI facilities at leading research institutions nationwide. Arrested development: When cells make mistakes, One RING to fool them all: Shedding light on BRCA1 mutations, A new diagnostic strategy for prostate cancer, Requirement for p53 and p21 to sustain G2 arrest after DNA damage, Variation in cancer risk among tissues can be explained by the number of stem cell divisions, BRCA1 tumor suppression depends on BRCT phosphoprotein binding, but not its E3 ligase activity, Urine TMPRSS2:ERG fusion transcript stratifies prostate cancer risk in men with elevated serum PSA, Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND 4.0) International License. In “Activity 2,” students examine cards that list genetic mutations found in actual cancer patients.

These studies are beginning to reveal new ways of attacking cancer by targeting a largely hidden network of normal genes that cancer cells rely on for survival. Privacy Policy and Terms of Use, Learning Lens by Science in the Classroom is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 (CC BY-NC-ND 4.0) International License, Annotated research papers and accompanying teaching materials. Web site has extensive news and information on recent research … smoking); and some types of infections (ex. Anatomy & Physiology. We are currently looking for a highly motivated Laboratory Manager to support the lab of Dr. Keiko Torii at the University of Texas at Austin in Austin, Texas. Experience with planning and organizing team functions and coordinating ongoing team activity. ��$2�H)��Wk� �(��H#5ϸBau ��p��S�ӡ�n�� The Torii lab has a long-standing interest to unravel how plant stem cells function and contribute to growth and development, with specific emphasis on signal transduction pathways and underpinning genomic/epigenomic mechanisms. This activity guides the analysis of a published scientific figure from a study that investigated how males in a species of sexually cannibalistic spiders choose their mates.

... Cancer … Cancer has touched the lives of most people worldwide; it can begin in any tissue and start at any age. Requests for reasonable accommodation will be evaluated on an individual basis. 9K�9>P�-�XM2�'G�/F�aۏH�� P;�G��F��R��D��ِ��i8��^��A�՚uP*��B��/"l�@yƧժ��j?��ȼ �p��Gc��~Y��I��F� Start studying HHMI: Cell Cycle and Cancer Click & Learn.

Exceptional ability to be proactive and goal-oriented in organizing and overseeing lab operations. West Nile Virus: Vectors and Hosts Game.

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HHMI is a science philanthropy whose mission is to advance basic biomedical research and science education for the benefit of humanity. This job description sets forth the job’s principal duties, responsibilities, and requirements; it should not be construed as an exhaustive statement, however. Our Scientists. Many people, including scientists, hoped that the sequencing of the human genome and easier accessibility to advanced technology would quickly result in an understanding of cancers, leading to a set of cures. HPV, which is a virus, or H. pylori, which is a bacteria).

Sequencing HHMI BioInteractive Cancer Resources In this article, Rocky Mountain College professor Holly Basta discusses how she sequences BioInteractive cancer resources to get her students to think about big questions in how cell division is regulated — and how understanding regulation can guide drug design. All rights reserved. David Knuffke describes how he uses BioInteractive's cancer activities in his classroom, and how they can help teach Mendelian genetics using an interactive, real-world example. Overview ; History ; Leadership ; Governance ; Financials ; Careers ; Policies ; For Our Hosts ; Doing Business with HHMI ; Our Scientists .